| 18 Apr 2006 | | Marylebone Cricket Club Young Cricketers v Middlesex Second XI | Brunton Memorial Ground, Radlett | Results |
| 25 Apr 2006 | | Yorkshire Second XI v Durham Second XI | The Playing Field, Stamford Bridge | Results |
| 24 Apr 2006 | | Lancashire Second XI v Nottinghamshire Second XI | Emirates Old Trafford, Manchester | Results |
| 26 Apr 2006 | | Sussex Second XI v Marylebone Cricket Club Young Cricketers | New County Ground, Hove | Results |
| 02 May 2006 | | Warwickshire Second XI v Lancashire Second XI | Scorers, Shirley | Results |
| 03 May 2006 | | Derbyshire Second XI v Nottinghamshire Second XI | Christchurch Meadows, Belper | Results |
| 08 May 2006 | | Derbyshire Second XI v Yorkshire Second XI | Racecourse Ground, Derby | Results |
| 09 May 2006 | | Hampshire Second XI v Warwickshire Second XI | Utilita Bowl (Nursery), Southampton | Results |
| 09 May 2006 | | Surrey Second XI v Essex Second XI | The Kia Oval, Kennington | Results |
| 16 May 2006 | | Durham Second XI v Lancashire Second XI | Seat Unique Riverside Ground, Chester-le-Street | Results |
| 16 May 2006 | | Leicestershire Second XI v Warwickshire Second XI | Uptonsteel County Ground, Leicester | Results |
| 16 May 2006 | | Glamorgan Second XI v Middlesex Second XI | The Athletic Ground, Gowerton | Results |
| 17 May 2006 | | Surrey Second XI v Marylebone Cricket Club Young Cricketers | The Ridge, Purley | Results |
| 23 May 2006 | | Yorkshire Second XI v Surrey Second XI | Clifton Park, York | Results |
| 23 May 2006 | | Nottinghamshire Second XI v Lancashire Second XI | Caythorpe Road, Caythorpe | Results |
| 24 May 2006 | | Leicestershire Second XI v Derbyshire Second XI | Leicester Road, Hinckley | Results |
| 24 May 2006 | | Marylebone Cricket Club Young Cricketers v Hampshire Second XI | Royal Air Force Sports Ground, Uxbridge | Results |
| 30 May 2006 | | Middlesex Second XI v Essex Second XI | Uxbridge Cricket Club Ground, Uxbridge | Results |
| 30 May 2006 | | Worcestershire Second XI v Warwickshire Second XI | Chester Road North, Kidderminster | Results |
| 31 May 2006 | | Hampshire Second XI v Yorkshire Second XI | Utilita Bowl (Nursery), Southampton | Results |
| 31 May 2006 | | Gloucestershire Second XI v Marylebone Cricket Club Young Cricketers | College Ground, Cheltenham | Results |
| 31 May 2006 | | Leicestershire Second XI v Surrey Second XI | Upper Field, Uppingham School | Results |
| 31 May 2006 | | Somerset Second XI v Glamorgan Second XI | Taunton Vale Sports Club Ground, Taunton | Results |
| 05 Jun 2006 | | Sussex Second XI v Yorkshire Second XI | New County Ground, Hove | Results |
| 06 Jun 2006 | | Derbyshire Second XI v Warwickshire Second XI | Deer Park, Dunstall | Results |
| 06 Jun 2006 | | Durham Second XI v Marylebone Cricket Club Young Cricketers | Longhirst Hall Ground, Longhirst | Results |
| 06 Jun 2006 | | Surrey Second XI v Middlesex Second XI | Park Lane, Reigate | Results |
| 06 Jun 2006 | | Gloucestershire Second XI v Nottinghamshire Second XI | Seat Unique Stadium, Bristol | Results |
| 06 Jun 2006 | | Lancashire Second XI v Hampshire Second XI | Emirates Old Trafford, Manchester | Results |
| 06 Jun 2006 | | Northamptonshire Second XI v Leicestershire Second XI | County Ground, Northampton | Results |
| 13 Jun 2006 | | Warwickshire Second XI v Surrey Second XI | Station Road, Dorridge | Results |
| 13 Jun 2006 | | Durham Second XI v Worcestershire Second XI | Derwenthaugh Park, Swalwell | Results |
| 13 Jun 2006 | | Yorkshire Second XI v Northamptonshire Second XI | Headingley, Leeds | Results |
| 14 Jun 2006 | | Lancashire Second XI v Gloucestershire Second XI | Stanley Park, Blackpool | Results |
| 20 Jun 2006 | | Yorkshire Second XI v Lancashire Second XI | Headingley, Leeds | Results |
| 20 Jun 2006 | | Northamptonshire Second XI v Durham Second XI | Stowe School Ground, Stowe | Results |
| 20 Jun 2006 | | Surrey Second XI v Glamorgan Second XI | Peaches Close, Cheam | Results |
| 27 Jun 2006 | | Durham Second XI v Leicestershire Second XI | The Racecourse, Durham | Results |
| 11 Jul 2006 | | Derbyshire Second XI v Lancashire Second XI | Racecourse Ground, Derby | Results |
| 18 Jul 2006 | | Essex Second XI v Middlesex Second XI | Hare Field, Coggeshall | Results |
| 18 Jul 2006 | | Surrey Second XI v Worcestershire Second XI | Whitgift School, Croydon | Results |
| 18 Jul 2006 | | Sussex Second XI v Warwickshire Second XI | The Pavilion, Birdham | Results |
| 25 Jul 2006 | | Derbyshire Second XI v Marylebone Cricket Club Young Cricketers | Christchurch Meadows, Belper | Results |
| 25 Jul 2006 | | Yorkshire Second XI v Warwickshire Second XI | The Playing Field, Stamford Bridge | Results |
| 26 Jul 2006 | | Sussex Second XI v Middlesex Second XI | Cricket Field Road, Horsham | Results |
| 26 Jul 2006 | | Surrey Second XI v Nottinghamshire Second XI | Cheam Road, Sutton | Results |
| 26 Jul 2006 | | Gloucestershire Second XI v Northamptonshire Second XI | Seat Unique Stadium, Bristol | Results |
| 26 Jul 2006 | | Kent Second XI v Essex Second XI | The Kent County Cricket Ground, Beckenham | Results |
| 01 Aug 2006 | | Marylebone Cricket Club Young Cricketers v Kent Second XI | Royal Air Force Sports Ground, Uxbridge | Results |
| 01 Aug 2006 | | Surrey Second XI v Durham Second XI | Woodbridge Road, Guildford | Results |
| 01 Aug 2006 | | Somerset Second XI v Gloucestershire Second XI | Willis Lane, North Perrott | Results |
| 01 Aug 2006 | | Hampshire Second XI v Essex Second XI | Utilita Bowl, Southampton | Results |
| 02 Aug 2006 | | Lancashire Second XI v Glamorgan Second XI | Moor Park, Great Crosby | Results |
| 02 Aug 2006 | | Northamptonshire Second XI v Middlesex Second XI | County Ground, Northampton | Results |
| 02 Aug 2006 | | Leicestershire Second XI v Sussex Second XI | Leicester Road, Hinckley | Results |
| 08 Aug 2006 | | Worcestershire Second XI v Marylebone Cricket Club Young Cricketers | Cherry Hill Road, Barnt Green | Results |
| 09 Aug 2006 | | Nottinghamshire Second XI v Kent Second XI | Nottinghamshire Sports Ground, Nottingham | Results |
| 09 Aug 2006 | | Durham Second XI v Derbyshire Second XI | Roseworth Terrace, Gosforth | Results |
| 09 Aug 2006 | | Hampshire Second XI v Surrey Second XI | Utilita Bowl, Southampton | Results |
| 09 Aug 2006 | | Somerset Second XI v Yorkshire Second XI | The Cooper Associates County Ground, Taunton | Results |
| 09 Aug 2006 | | Essex Second XI v Leicestershire Second XI | The Toby Howe Cricket Ground, Billericay | Results |
| 09 Aug 2006 | | Warwickshire Second XI v Northamptonshire Second XI | Swans Nest Lane, Stratford-upon-Avon | Results |
| 15 Aug 2006 | | Durham Second XI v Yorkshire Second XI | Seat Unique Riverside Ground, Chester-le-Street | Results |
| 15 Aug 2006 | | Northamptonshire Second XI v Surrey Second XI | Campbell Park, Milton Keynes | Results |
| 15 Aug 2006 | | Glamorgan Second XI v Leicestershire Second XI | Panteg House, Griffithstown | Results |
| 15 Aug 2006 | | Middlesex Second XI v Somerset Second XI | Merchant Taylors' School Ground, Northwood | Results |
| 16 Aug 2006 | | Gloucestershire Second XI v Hampshire Second XI | Gordon Road Playing Field, Bristol | Results |
| 16 Aug 2006 | | Worcestershire Second XI v Lancashire Second XI | Visit Worcestershire New Road, Worcester | Results |
| 16 Aug 2006 | | Sussex Second XI v Derbyshire Second XI | The Pavilion, Birdham | Results |
| 21 Aug 2006 | | Middlesex Second XI v Derbyshire Second XI | John Walker's Ground, Southgate | Results |
| 22 Aug 2006 | | Essex Second XI v Warwickshire Second XI | Cricketfield Lane, Bishop's Stortford | Results |
| 22 Aug 2006 | | Kent Second XI v Worcestershire Second XI | Spitfire Ground, St Lawrence, Canterbury | Results |
| 22 Aug 2006 | | Hampshire Second XI v Somerset Second XI | May's Bounty, Basingstoke | Results |
| 22 Aug 2006 | | Nottinghamshire Second XI v Durham Second XI | Worksop College Ground, Worksop | Results |
| 22 Aug 2006 | | Surrey Second XI v Sussex Second XI | Church Road, Wimbledon | Results |
| 22 Aug 2006 | | Leicestershire Second XI v Yorkshire Second XI | Uptonsteel County Ground, Leicester | Results |
| 23 Aug 2006 | | Marylebone Cricket Club Young Cricketers v Northamptonshire Second XI | Brunton Memorial Ground, Radlett | Results |
| 29 Aug 2006 | | Middlesex Second XI v Yorkshire Second XI | Uxbridge Cricket Club Ground, Uxbridge | Results |
| 29 Aug 2006 | | Hampshire Second XI v Kent Second XI | Utilita Bowl (Nursery), Southampton | Results |
| 29 Aug 2006 | | Lancashire Second XI v Surrey Second XI | Trafalgar Road, Southport | Results |
| 29 Aug 2006 | | Leicestershire Second XI v Marylebone Cricket Club Young Cricketers | Leicester Road, Hinckley | Results |
| 30 Aug 2006 | | Warwickshire Second XI v Durham Second XI | The John Findlay Memorial Ground, Walmley | Results |
| 30 Aug 2006 | | Northamptonshire Second XI v Nottinghamshire Second XI | County Ground, Northampton | Results |
| 30 Aug 2006 | | Derbyshire Second XI v Gloucestershire Second XI | Queen's Park, Chesterfield | Results |
| 06 Sep 2006 | | Essex Second XI v Sussex Second XI | Star Stile, Halstead | Results |
| 06 Sep 2006 | | Marylebone Cricket Club Young Cricketers v Durham Second XI | Brunton Memorial Ground, Radlett | Results |
| 06 Sep 2006 | | Lancashire Second XI v Yorkshire Second XI | Centre Vale, Todmorden | Results |
| 06 Sep 2006 | | Kent Second XI v Surrey Second XI | The Kent County Cricket Ground, Beckenham | Results |
| 06 Sep 2006 | | Glamorgan Second XI v Gloucestershire Second XI | Lower Mill Street, Usk | Results |
| 06 Sep 2006 | | Warwickshire Second XI v Hampshire Second XI | Glasshouse Park, Kenilworth | Results |
| 12 Sep 2006 | | Yorkshire Second XI v Essex Second XI | The Playing Field, Stamford Bridge | Results |
| 12 Sep 2006 | | Worcestershire Second XI v Sussex Second XI | Cherry Hill Road, Barnt Green | Results |
| 11 Sep 2006 | | Nottinghamshire Second XI v Somerset Second XI | Nottinghamshire Sports Ground, Nottingham | Results |
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