| 22 May 2022 | Preliminary Round | Sherborne Pilgrims v Old Brightonians | Sherborne School, Sherborne | Results |
| 22 May 2022 | Preliminary Round | Old Malvernians v Old Millfieldians | Malvern College Ground, Malvern | Results |
| 12 Jun 2022 | First Round | Shrewsbury Saracens v St Edward's Martyrs | Shrewsbury School, Shrewsbury | Results |
| 12 Jun 2022 | First Round | Old Alleynians v Harrow Wanderers | Dulwich College Ground, Dulwich | Results |
| 12 Jun 2022 | First Round | Old Brightonians v Old Merchant Taylors | Brighton College Ground, Brighton | Results |
| 12 Jun 2022 | First Round | Old Amplefordians v Old Cheltonians | Ampleforth College, Ampleforth | Results |
| 12 Jun 2022 | First Round | Old Cliftonians v Stowe Templars | Clifton College Close Ground, Clifton | Results |
| 12 Jun 2022 | First Round | Lancing Rovers v Old Tonbridgians | Lancing College Ground, Lancing | Results |
| 12 Jun 2022 | First Round | Marlborough Blues v Bradfield Waifs | Marlborough College Ground, Marlborough | Results |
| 12 Jun 2022 | First Round | Eton Ramblers v Felsted Robins | Upper Club, Eton College | Results |
| 12 Jun 2022 | First Round | Haileybury Hermits v Old Wellingtonians | Haileybury College Ground, Hertford | Results |
| 12 Jun 2022 | First Round | Old Eastbournians v Old Hurst Johnians | Eastbourne College Ground, Eastbourne | Results |
| 12 Jun 2022 | First Round | Downside Wanderers v Old Cranleighans | Downside School, Stratton-on-the-Fosse | Results |
| 12 Jun 2022 | First Round | Uppingham Rovers v Old Bedfordians | Upper Field, Uppingham School | Results |
| 12 Jun 2022 | First Round | Old Wykehamists v Rugby Meteors | Ridding Field, Winchester | Results |
| 12 Jun 2022 | First Round | Oundle Rovers v Repton Pilgrims | Oundle School Ground, Oundle | Results |
| 12 Jun 2022 | First Round | Radley Rangers v Old Cholmeleians | Radley College Bigside Ground, Abingdon | Results |
| 12 Jun 2022 | First Round | Old Millfieldians v Charterhouse Friars | Millfield School, Street | Results |
| 26 Jun 2022 | Second Round | Bradfield Waifs v Eton Ramblers | Bradfield College, Reading | Results |
| 26 Jun 2022 | Second Round | Old Wellingtonians v Old Hurst Johnians | Wellington College, Crowthorne | Results |
| 26 Jun 2022 | Second Round | Rugby Meteors v Oundle Rovers | Rugby School Ground, Rugby | Results |
| 26 Jun 2022 | Second Round | Shrewsbury Saracens v Harrow Wanderers | Shrewsbury School, Shrewsbury | Results |
| 26 Jun 2022 | Second Round | Old Cliftonians v Lancing Rovers | Clifton College Close Ground, Clifton | Results |
| 26 Jun 2022 | Second Round | Old Cranleighans v Uppingham Rovers | Jubilee, Cranleigh School | Results |
| 26 Jun 2022 | Second Round | Radley Rangers v Old Millfieldians | Radley College Bigside Ground, Abingdon | Results |
| 26 Jun 2022 | Second Round | Old Merchant Taylors v Old Cheltonians | Merchant Taylors' School Ground, Northwood | Results |
| 10 Jul 2022 | Quarter-Final | Old Wellingtonians v Old Cranleighans | Wellington College, Crowthorne | Results |
| 10 Jul 2022 | Quarter-Final | Lancing Rovers v Bradfield Waifs | Lancing College Ground, Lancing | Results |
| 10 Jul 2022 | Quarter-Final | Shrewsbury Saracens v Old Cheltonians | Shrewsbury School, Shrewsbury | Results |
| 10 Jul 2022 | Quarter-Final | Oundle Rovers v Old Millfieldians | Oundle School Ground, Oundle | Results |
| 24 Jul 2022 | Semi-Final | Old Cheltonians v Bradfield Waifs | College Ground, Cheltenham | Results |
| 24 Jul 2022 | Semi-Final | Old Wellingtonians v Old Millfieldians | Wellington College, Crowthorne | Results |
| 07 Aug 2022 | Final | Bradfield Waifs v Old Millfieldians | Arundel Castle Cricket Club Ground, Arundel | Results |
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