| 22 May 2005 | First Round | Langley Mill United v Old Derbeians | Station Road, Langley Mill | Results |
| 22 May 2005 | First Round | Lullington Park Third XI v Sandiacre Town Third XI | Lullington Park Pitch 2, Lullington | Results |
| 22 May 2005 | First Round | Marehay Second XI v Belper Amateurs | The Maryfield, Ripley | Results |
| 22 May 2005 | First Round | Mickleover v Darley Abbey Second XI | Station Road, Mickleover | Results |
| 22 May 2005 | First Round | Ockbrook and Borrowash Third XI v Duffield Second XI | Victoria Avenue Pitch 2, Ockbrook | Results |
| 22 May 2005 | First Round | Parwich v Little Eaton | Parwich Cricket Club Ground, Parwich | Results |
| 22 May 2005 | First Round | Rolls Royce Second XI v Butterley United | Rolls Royce Ground, Derby | Results |
| 22 May 2005 | First Round | Sawley and Long Eaton Park Third XI v Clowne Town | West Park, Long Eaton | Results |
| 22 May 2005 | First Round | South Wingfield Second XI v Cromford Meadows | Holme Lane, South Wingfield | Results |
| 22 May 2005 | First Round | Swarkestone Second XI v Whitmoor Rowing Club | Barrow Turn, Swarkestone | Results |
| 22 May 2005 | First Round | Wingerworth v Rosehill Methodists | Deer Park, Wingerworth | Results |
| 22 May 2005 | First Round | Alfreton Second XI v Brailsford and Ednaston Second XI | Alfreton Park, Alfreton | Results |
| 22 May 2005 | First Round | Aston-on-Trent Second XI v Denby Third XI | Shardlow Road, Aston-on-Trent | Results |
| 22 May 2005 | First Round | Codnor v Tibshelf | Goose Lane, Codnor | Results |
| 22 May 2005 | First Round | Elvaston Third XI v Riddings Second XI | Stable Drive, Elvaston | Results |
| 22 May 2005 | First Round | Kirk Langley v Tutbury Second XI | Barrington Playing Fields, Kirk Langley | Results |
| 19 Jun 2005 | Second Round | Elvaston Third XI v Alfreton Second XI | Stable Drive, Elvaston | Results |
| 19 Jun 2005 | Second Round | Langley Mill United v Tibshelf | Station Road, Langley Mill | Results |
| 19 Jun 2005 | Second Round | Mickleover v Duffield Second XI | Station Road, Mickleover | Results |
| 19 Jun 2005 | Second Round | Sawley and Long Eaton Park Third XI v Rolls Royce Second XI | West Park, Long Eaton | Results |
| 26 Jun 2005 | Second Round | Belper Amateurs v Whitmoor Rowing Club | The Packhorse Ground, Alderwasley | Results |
| 26 Jun 2005 | Second Round | Parwich v South Wingfield Second XI | Parwich Cricket Club Ground, Parwich | Results |
| 19 Jun 2005 | Second Round | Tutbury Second XI v Lullington Park Third XI | Tutbury Mill, Tutbury | Results |
| 26 Jun 2005 | Second Round | Tutbury Second XI v Lullington Park Third XI | Tutbury Mill, Tutbury | Results |
| 26 Jun 2005 | Second Round | Wingerworth v Aston-on-Trent Second XI | Deer Park, Wingerworth | Results |
| 10 Jul 2005 | Quarter-Final | Alfreton Second XI v Duffield Second XI | Alfreton Park, Alfreton | Results |
| 10 Jul 2005 | Quarter-Final | Aston-on-Trent Second XI v Langley Mill United | Shardlow Road, Aston-on-Trent | Results |
| 10 Jul 2005 | Quarter-Final | Belper Amateurs v Sawley and Long Eaton Park Third XI | The Packhorse Ground, Alderwasley | Results |
| 10 Jul 2005 | Quarter-Final | South Wingfield Second XI v Tutbury Second XI | Holme Lane, South Wingfield | Results |
| 31 Jul 2005 | Semi-Final | Belper Amateurs v Duffield Second XI | The Packhorse Ground, Alderwasley | Results |
| 31 Jul 2005 | Semi-Final | South Wingfield Second XI v Langley Mill United | Holme Lane, South Wingfield | Results |
| 21 Aug 2005 | Final | Langley Mill United v Belper Amateurs | Station Road, Langley Mill | Results |
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