| 05 May 1906 | | St Helens Recreation v Newton-le-Willows | The Oval, St Helens | Results |
| 05 May 1906 | | Stanley v Warrington | Stanley Park, Liverpool | Results |
| 12 May 1906 | | Newton-le-Willows v Earlestown | Crow Lane East, Newton-le-Willows | Results |
| 12 May 1906 | | Prescot v St Helens Recreation | Burrows Lane, Prescot | Results |
| 19 May 1906 | | Earlestown v Prescot | Viaduct Green, Earlestown | Results |
| 19 May 1906 | | St Helens Recreation v Stanley | The Oval, St Helens | Results |
| 19 May 1906 | | Warrington v St Helens | Walton Lea Road, Warrington | Results |
| 26 May 1906 | | St Helens v Earlestown | Windleshaw Road, St Helens | Results |
| 26 May 1906 | | Warrington v St Helens Recreation | Walton Lea Road, Warrington | Results |
| 02 Jun 1906 | | St Helens Recreation v Prescot | The Oval, St Helens | Results |
| 02 Jun 1906 | | Stanley v St Helens | Stanley Park, Liverpool | Results |
| 02 Jun 1906 | | Warrington v Newton-le-Willows | Walton Lea Road, Warrington | Results |
| 09 Jun 1906 | | Earlestown v St Helens | Viaduct Green, Earlestown | Results |
| 09 Jun 1906 | | Newton-le-Willows v Stanley | Crow Lane East, Newton-le-Willows | Results |
| 09 Jun 1906 | | Warrington v Prescot | Walton Lea Road, Warrington | Results |
| 16 Jun 1906 | | Earlestown v Warrington | Viaduct Green, Earlestown | Results |
| 16 Jun 1906 | | Prescot v Stanley | Burrows Lane, Prescot | Results |
| 16 Jun 1906 | | St Helens v Newton-le-Willows | Windleshaw Road, St Helens | Results |
| 23 Jun 1906 | | St Helens Recreation v Warrington | The Oval, St Helens | Results |
| 23 Jun 1906 | | Stanley v Earlestown | Stanley Park, Liverpool | Results |
| 30 Jun 1906 | | Earlestown v Newton-le-Willows | Viaduct Green, Earlestown | Results |
| 30 Jun 1906 | | St Helens v Prescot | Windleshaw Road, St Helens | Results |
| 30 Jun 1906 | | Stanley v St Helens Recreation | Stanley Park, Liverpool | Results |
| 07 Jul 1906 | | Earlestown v St Helens Recreation | Viaduct Green, Earlestown | Results |
| 07 Jul 1906 | | Newton-le-Willows v Prescot | Crow Lane East, Newton-le-Willows | Results |
| 07 Jul 1906 | | Warrington v Stanley | Walton Lea Road, Warrington | Results |
| 14 Jul 1906 | | Newton-le-Willows v Warrington | Crow Lane East, Newton-le-Willows | Results |
| 14 Jul 1906 | | Prescot v Earlestown | Burrows Lane, Prescot | Results |
| 14 Jul 1906 | | St Helens v Stanley | Windleshaw Road, St Helens | Results |
| 21 Jul 1906 | | Prescot v Newton-le-Willows | Burrows Lane, Prescot | Results |
| 21 Jul 1906 | | St Helens Recreation v St Helens | The Oval, St Helens | Results |
| 21 Jul 1906 | | Warrington v Earlestown | Walton Lea Road, Warrington | Results |
| 28 Jul 1906 | | Newton-le-Willows v St Helens Recreation | Crow Lane East, Newton-le-Willows | Results |
| 28 Jul 1906 | | St Helens v Warrington | Windleshaw Road, St Helens | Results |
| 28 Jul 1906 | | Stanley v Prescot | Stanley Park, Liverpool | Results |
| 04 Aug 1906 | | Earlestown v Stanley | Viaduct Green, Earlestown | Results |
| 04 Aug 1906 | | Prescot v St Helens | Burrows Lane, Prescot | Results |
| 11 Aug 1906 | | St Helens v St Helens Recreation | Windleshaw Road, St Helens | Results |
| 11 Aug 1906 | | Stanley v Newton-le-Willows | Stanley Park, Liverpool | Results |
| 18 Aug 1906 | | Newton-le-Willows v St Helens | Crow Lane East, Newton-le-Willows | Results |
| 18 Aug 1906 | | Prescot v Warrington | Burrows Lane, Prescot | Results |
| 18 Aug 1906 | | St Helens Recreation v Earlestown | The Oval, St Helens | Results |
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