| 01 May 2010 | | Cuckfield v Eastbourne | Cuckfield Park, Cuckfield | Results |
| 01 May 2010 | | Bexhill v Hastings and St Leonards Priory | The Polegrove, Bexhill-on-Sea | Results |
| 01 May 2010 | | Three Bridges v East Grinstead | Three Bridges Road, Three Bridges | Results |
| 01 May 2010 | | Chichester Priory Park v Horsham | Chichester Priory Park, Chichester | Results |
| 01 May 2010 | | Preston Nomads v Brighton and Hove | Spen Cama Memorial Ground, Fulking | Results |
| 08 May 2010 | | Brighton and Hove v Chichester Priory Park | Nevill Sports Ground, Hove | Results |
| 08 May 2010 | | Eastbourne v Preston Nomads | The Saffrons, Eastbourne | Results |
| 08 May 2010 | | Cuckfield v Three Bridges | Cuckfield Park, Cuckfield | Results |
| 08 May 2010 | | East Grinstead v Bexhill | East Grinstead Sports Club Ground, East Grinstead | Results |
| 08 May 2010 | | Horsham v Hastings and St Leonards Priory | Cricket Field Road, Horsham | Results |
| 09 May 2010 | | Cuckfield v Sussex Development XI | Cuckfield Park, Cuckfield | Results |
| 15 May 2010 | | Bexhill v Cuckfield | The Polegrove, Bexhill-on-Sea | Results |
| 15 May 2010 | | Brighton and Hove v Horsham | Nevill Sports Ground, Hove | Results |
| 15 May 2010 | | Chichester Priory Park v Eastbourne | Chichester Priory Park, Chichester | Results |
| 15 May 2010 | | Hastings and St Leonards Priory v East Grinstead | Horntye Park, Hastings | Results |
| 15 May 2010 | | Preston Nomads v Three Bridges | Spen Cama Memorial Ground, Fulking | Results |
| 22 May 2010 | | Cuckfield v Hastings and St Leonards Priory | Cuckfield Park, Cuckfield | Results |
| 22 May 2010 | | Eastbourne v Brighton and Hove | The Saffrons, Eastbourne | Results |
| 22 May 2010 | | Horsham v East Grinstead | Cricket Field Road, Horsham | Results |
| 22 May 2010 | | Preston Nomads v Bexhill | Spen Cama Memorial Ground, Fulking | Results |
| 22 May 2010 | | Three Bridges v Chichester Priory Park | Three Bridges Road, Three Bridges | Results |
| 23 May 2010 | | Chichester Priory Park v Sussex Development XI | Chichester Priory Park, Chichester | Results |
| 29 May 2010 | | Brighton and Hove v Three Bridges | Nevill Sports Ground, Hove | Results |
| 29 May 2010 | | Chichester Priory Park v Bexhill | Chichester Priory Park, Chichester | Results |
| 29 May 2010 | | East Grinstead v Cuckfield | East Grinstead Sports Club Ground, East Grinstead | Results |
| 29 May 2010 | | Eastbourne v Horsham | The Saffrons, Eastbourne | Results |
| 29 May 2010 | | Hastings and St Leonards Priory v Preston Nomads | Horntye Park, Hastings | Results |
| 01 Aug 2010 | | Brighton and Hove v Sussex Development XI | Nevill Sports Ground, Hove | Results |
| 05 Jun 2010 | | Bexhill v Brighton and Hove | The Polegrove, Bexhill-on-Sea | Results |
| 05 Jun 2010 | | Chichester Priory Park v Hastings and St Leonards Priory | Chichester Priory Park, Chichester | Results |
| 05 Jun 2010 | | Horsham v Cuckfield | Cricket Field Road, Horsham | Results |
| 05 Jun 2010 | | Preston Nomads v East Grinstead | Spen Cama Memorial Ground, Fulking | Results |
| 05 Jun 2010 | | Three Bridges v Eastbourne | Three Bridges Road, Three Bridges | Results |
| 12 Jun 2010 | | Brighton and Hove v Hastings and St Leonards Priory | Nevill Sports Ground, Hove | Results |
| 12 Jun 2010 | | Cuckfield v Preston Nomads | Cuckfield Park, Cuckfield | Results |
| 12 Jun 2010 | | East Grinstead v Chichester Priory Park | East Grinstead Sports Club Ground, East Grinstead | Results |
| 12 Jun 2010 | | Eastbourne v Bexhill | The Saffrons, Eastbourne | Results |
| 12 Jun 2010 | | Three Bridges v Horsham | Three Bridges Road, Three Bridges | Results |
| 13 Jun 2010 | | East Grinstead v Sussex Development XI | East Grinstead Sports Club Ground, East Grinstead | Results |
| 19 Jun 2010 | | Bexhill v Three Bridges | The Polegrove, Bexhill-on-Sea | Results |
| 19 Jun 2010 | | Brighton and Hove v East Grinstead | Nevill Sports Ground, Hove | Results |
| 19 Jun 2010 | | Chichester Priory Park v Cuckfield | Chichester Priory Park, Chichester | Results |
| 19 Jun 2010 | | Hastings and St Leonards Priory v Eastbourne | Horntye Park, Hastings | Results |
| 19 Jun 2010 | | Horsham v Preston Nomads | Cricket Field Road, Horsham | Results |
| 26 Jun 2010 | | Bexhill v Horsham | The Polegrove, Bexhill-on-Sea | Results |
| 26 Jun 2010 | | Cuckfield v Brighton and Hove | Cuckfield Park, Cuckfield | Results |
| 26 Jun 2010 | | Eastbourne v East Grinstead | The Saffrons, Eastbourne | Results |
| 26 Jun 2010 | | Preston Nomads v Chichester Priory Park | Spen Cama Memorial Ground, Fulking | Results |
| 27 Jun 2010 | | Bexhill v Sussex Development XI | The Polegrove, Bexhill-on-Sea | Results |
| 03 Jul 2010 | | Brighton and Hove v Preston Nomads | Nevill Sports Ground, Hove | Results |
| 03 Jul 2010 | | East Grinstead v Three Bridges | East Grinstead Sports Club Ground, East Grinstead | Results |
| 03 Jul 2010 | | Eastbourne v Cuckfield | The Saffrons, Eastbourne | Results |
| 03 Jul 2010 | | Hastings and St Leonards Priory v Bexhill | Horntye Park, Hastings | Results |
| 03 Jul 2010 | | Horsham v Chichester Priory Park | Cricket Field Road, Horsham | Results |
| 04 Jul 2010 | | Horsham v Sussex Development XI | Cricket Field Road, Horsham | Results |
| 10 Jul 2010 | | Bexhill v East Grinstead | The Polegrove, Bexhill-on-Sea | Results |
| 10 Jul 2010 | | Hastings and St Leonards Priory v Horsham | Horntye Park, Hastings | Results |
| 10 Jul 2010 | | Preston Nomads v Eastbourne | Spen Cama Memorial Ground, Fulking | Results |
| 10 Jul 2010 | | Three Bridges v Cuckfield | Three Bridges Road, Three Bridges | Results |
| 17 Jul 2010 | | Cuckfield v Bexhill | Cuckfield Park, Cuckfield | Results |
| 17 Jul 2010 | | East Grinstead v Hastings and St Leonards Priory | East Grinstead Sports Club Ground, East Grinstead | Results |
| 17 Jul 2010 | | Eastbourne v Chichester Priory Park | The Saffrons, Eastbourne | Results |
| 17 Jul 2010 | | Horsham v Brighton and Hove | Cricket Field Road, Horsham | Results |
| 17 Jul 2010 | | Three Bridges v Preston Nomads | Three Bridges Road, Three Bridges | Results |
| 18 Jul 2010 | | Preston Nomads v Sussex Development XI | Spen Cama Memorial Ground, Fulking | Results |
| 24 Jul 2010 | | Brighton and Hove v Eastbourne | Nevill Sports Ground, Hove | Results |
| 24 Jul 2010 | | Chichester Priory Park v Three Bridges | Chichester Priory Park, Chichester | Results |
| 24 Jul 2010 | | East Grinstead v Horsham | East Grinstead Sports Club Ground, East Grinstead | Results |
| 24 Jul 2010 | | Hastings and St Leonards Priory v Cuckfield | Horntye Park, Hastings | Results |
| 25 Jul 2010 | | Three Bridges v Sussex Development XI | Three Bridges Road, Three Bridges | Results |
| 31 Jul 2010 | | Bexhill v Chichester Priory Park | The Polegrove, Bexhill-on-Sea | Results |
| 31 Jul 2010 | | Cuckfield v East Grinstead | Cuckfield Park, Cuckfield | Results |
| 31 Jul 2010 | | Horsham v Eastbourne | Cricket Field Road, Horsham | Results |
| 31 Jul 2010 | | Preston Nomads v Hastings and St Leonards Priory | Spen Cama Memorial Ground, Fulking | Results |
| 31 Jul 2010 | | Three Bridges v Brighton and Hove | Three Bridges Road, Three Bridges | Results |
| 07 Aug 2010 | | Brighton and Hove v Bexhill | Nevill Sports Ground, Hove | Results |
| 07 Aug 2010 | | East Grinstead v Preston Nomads | East Grinstead Sports Club Ground, East Grinstead | Results |
| 07 Aug 2010 | | Eastbourne v Three Bridges | The Saffrons, Eastbourne | Results |
| 07 Aug 2010 | | Hastings and St Leonards Priory v Chichester Priory Park | Horntye Park, Hastings | Results |
| 08 Aug 2010 | | Hastings and St Leonards Priory v Sussex Development XI | Horntye Park, Hastings | Results |
| 14 Aug 2010 | | Bexhill v Eastbourne | The Polegrove, Bexhill-on-Sea | Results |
| 14 Aug 2010 | | Chichester Priory Park v East Grinstead | Chichester Priory Park, Chichester | Results |
| 14 Aug 2010 | | Hastings and St Leonards Priory v Brighton and Hove | Horntye Park, Hastings | Results |
| 14 Aug 2010 | | Horsham v Three Bridges | Cricket Field Road, Horsham | Results |
| 14 Aug 2010 | | Preston Nomads v Cuckfield | Spen Cama Memorial Ground, Fulking | Results |
| 21 Aug 2010 | | Cuckfield v Chichester Priory Park | Cuckfield Park, Cuckfield | Results |
| 21 Aug 2010 | | East Grinstead v Brighton and Hove | East Grinstead Sports Club Ground, East Grinstead | Results |
| 21 Aug 2010 | | Eastbourne v Hastings and St Leonards Priory | The Saffrons, Eastbourne | Results |
| 21 Aug 2010 | | Preston Nomads v Horsham | Spen Cama Memorial Ground, Fulking | Results |
| 21 Aug 2010 | | Three Bridges v Bexhill | Three Bridges Road, Three Bridges | Results |
| 22 Aug 2010 | | Eastbourne v Sussex Development XI | The Saffrons, Eastbourne | Results |
| 28 Aug 2010 | | Brighton and Hove v Cuckfield | Nevill Sports Ground, Hove | Results |
| 28 Aug 2010 | | Chichester Priory Park v Preston Nomads | Chichester Priory Park, Chichester | Results |
| 28 Aug 2010 | | Hastings and St Leonards Priory v Three Bridges | Horntye Park, Hastings | Results |
| 28 Aug 2010 | | Horsham v Bexhill | Cricket Field Road, Horsham | Results |
| 04 Sep 2010 | | Bexhill v Preston Nomads | The Polegrove, Bexhill-on-Sea | Results |
| 04 Sep 2010 | | Chichester Priory Park v Brighton and Hove | Chichester Priory Park, Chichester | Results |
| 04 Sep 2010 | | Cuckfield v Horsham | Cuckfield Park, Cuckfield | Results |
| 04 Sep 2010 | | East Grinstead v Eastbourne | East Grinstead Sports Club Ground, East Grinstead | Results |
| 04 Sep 2010 | | Three Bridges v Hastings and St Leonards Priory | Three Bridges Road, Three Bridges | Results |
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